Metabolism of macromolecules in tissue.
Identifieur interne : 008E44 ( Main/Exploration ); précédent : 008E43; suivant : 008E45Metabolism of macromolecules in tissue.
Auteurs : Ningfei Liu [République populaire de Chine]Source :
- Lymphatic research and biology [ 1539-6851 ] ; 2003.
Descripteurs français
- KwdFr :
- Acide hyaluronique (métabolisme), Animaux, Cicatrisation de plaie, Facteurs temps, Glycoprotéines (métabolisme), Humains, Inflammation, Lymphe (métabolisme), Lymphoedème (anatomopathologie), Mouvement cellulaire, Noeuds lymphatiques (anatomopathologie), Protéines du transport vésiculaire, Rats, Structures macromoléculaires (métabolisme), Système lymphatique (physiologie).
- MESH :
- anatomopathologie : Lymphoedème, Noeuds lymphatiques.
- métabolisme : Acide hyaluronique, Glycoprotéines, Lymphe, Structures macromoléculaires.
- physiologie : Système lymphatique.
- Animaux, Cicatrisation de plaie, Facteurs temps, Humains, Inflammation, Mouvement cellulaire, Protéines du transport vésiculaire, Rats.
English descriptors
- KwdEn :
- Animals, Cell Movement, Glycoproteins (metabolism), Humans, Hyaluronic Acid (metabolism), Inflammation, Lymph (metabolism), Lymph Nodes (pathology), Lymphatic System (physiology), Lymphedema (pathology), Macromolecular Substances (metabolism), Rats, Time Factors, Vesicular Transport Proteins, Wound Healing.
- MESH :
- chemical , metabolism : Glycoproteins, Hyaluronic Acid, Macromolecular Substances.
- metabolism : Lymph.
- pathology : Lymph Nodes, Lymphedema.
- physiology : Lymphatic System.
- Animals, Cell Movement, Humans, Inflammation, Rats, Time Factors, Vesicular Transport Proteins, Wound Healing.
Abstract
Hyaluronan (HA) plays an important role in maintaining tissue integrity, as well as in facilitating the migration of cells during inflammation, wound repair, and embryonic development. By comparison with other macromolecules of the extracellular matrix, HA undergoes rapid turnover. Most of its degradation does not occur locally, but within distant lymph nodes. During this process, tissue HA enters the afferent lymphatics and is transported with the lymph to the draining lymph nodes. Because of its unique catabolic pathway, the fate of HA is an interesting subject for investigation, particularly in pathological states of lymphangiodysplasia or lymphatic damage.
DOI: 10.1089/15396850360495718
PubMed: 15624323
Affiliations:
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Le document en format XML
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wicri:level="1"><nlm:affiliation>Department of Plastic Surgery, Ninth People's Hospital, Shanghai Second Medical University, PR China. liun2002@yahoo.com</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plastic Surgery, Ninth People's Hospital, Shanghai Second Medical University</wicri:regionArea><wicri:noRegion>Shanghai Second Medical University</wicri:noRegion></affiliation></author></analytic><series><title level="j">Lymphatic research and biology</title><idno type="ISSN">1539-6851</idno><imprint><date when="2003" type="published">2003</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Cell Movement</term><term>Glycoproteins (metabolism)</term><term>Humans</term><term>Hyaluronic Acid (metabolism)</term><term>Inflammation</term><term>Lymph (metabolism)</term><term>Lymph Nodes (pathology)</term><term>Lymphatic System (physiology)</term><term>Lymphedema (pathology)</term><term>Macromolecular Substances (metabolism)</term><term>Rats</term><term>Time Factors</term><term>Vesicular Transport Proteins</term><term>Wound Healing</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Acide hyaluronique (métabolisme)</term><term>Animaux</term><term>Cicatrisation de plaie</term><term>Facteurs temps</term><term>Glycoprotéines (métabolisme)</term><term>Humains</term><term>Inflammation</term><term>Lymphe (métabolisme)</term><term>Lymphoedème (anatomopathologie)</term><term>Mouvement cellulaire</term><term>Noeuds lymphatiques (anatomopathologie)</term><term>Protéines du transport vésiculaire</term><term>Rats</term><term>Structures macromoléculaires (métabolisme)</term><term>Système lymphatique (physiologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Glycoproteins</term><term>Hyaluronic Acid</term><term>Macromolecular Substances</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Lymphoedème</term><term>Noeuds lymphatiques</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Lymph</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Acide hyaluronique</term><term>Glycoprotéines</term><term>Lymphe</term><term>Structures macromoléculaires</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Lymph Nodes</term><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Système lymphatique</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Lymphatic System</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Cell Movement</term><term>Humans</term><term>Inflammation</term><term>Rats</term><term>Time Factors</term><term>Vesicular Transport Proteins</term><term>Wound Healing</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Cicatrisation de plaie</term><term>Facteurs temps</term><term>Humains</term><term>Inflammation</term><term>Mouvement cellulaire</term><term>Protéines du transport vésiculaire</term><term>Rats</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Hyaluronan (HA) plays an important role in maintaining tissue integrity, as well as in facilitating the migration of cells during inflammation, wound repair, and embryonic development. By comparison with other macromolecules of the extracellular matrix, HA undergoes rapid turnover. Most of its degradation does not occur locally, but within distant lymph nodes. During this process, tissue HA enters the afferent lymphatics and is transported with the lymph to the draining lymph nodes. Because of its unique catabolic pathway, the fate of HA is an interesting subject for investigation, particularly in pathological states of lymphangiodysplasia or lymphatic damage.</div></front></TEI><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Liu, Ningfei" sort="Liu, Ningfei" uniqKey="Liu N" first="Ningfei" last="Liu">Ningfei Liu</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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